Gout attacks can be precipitated by which dietary factor due to competition for excretion in the kidney?

Gout attacks can be precipitated by which dietary factor due to competition for excretion in the kidney?

• A. Alcohol
• B. Vitamin C
• C. Dairy products
• D. Fish oil

Answer: (A)

Gout attacks occur when uric acid builds up and crystals form in joints, and the kidneys play a key role in clearing uric acid from the blood. Substances that share the same renal excretion pathways can compete with uric acid for elimination. Alcohol metabolism increases lactate, which competes with uric acid for excretion in the kidney, reducing urate clearance. This leads to higher serum uric acid and a greater risk of a gout flare after drinking. So alcohol is the dietary factor most likely to precipitate an attack through this renal competition. Vitamin C tends to promote uric acid excretion and can lower urate levels, dairy products are low in purines and may be protective, and fish oil doesn’t have a significant impact on urate excretion.

Gout attacks occur when uric acid builds up and crystals form in joints, and the kidneys play a key role in clearing uric acid from the blood. Substances that share the same renal excretion pathways can compete with uric acid for elimination. Alcohol metabolism increases lactate, which competes with uric acid for excretion in the kidney, reducing urate clearance. This leads to higher serum uric acid and a greater risk of a gout flare after drinking. So alcohol is the dietary factor most likely to precipitate an attack through this renal competition. Vitamin C tends to promote uric acid excretion and can lower urate levels, dairy products are low in purines and may be protective, and fish oil doesn’t have a significant impact on urate excretion.